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2-Methoxyphenyl dihydrouracil-azaspiro[5.5]undecane-C-PIP

CAS: F: C27H39N5O4 W: 497.63

2-Methoxyphenyl dihydrouracil-azaspiroundecane-C-PIP is an E3 Ligase ligand-linker conjugate, and can be used for synthe
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Bioactivity 2-Methoxyphenyl dihydrouracil-azaspiro[5.5]undecane-C-PIP is an E3 Ligase ligand-linker conjugate, and can be used for synthesis of PROTAC SOS1 degrader-10 (HY-161654)[1].
Formula C27H39N5O4
Molar Mass 497.63
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Wang K, et al. Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor. Bioorg Med Chem Lett. 2024 Jul 15;107:129780.